Back to the peptide atlas
Tissue & repairPeptideIn clinical research

ARA-290 / Cibinetide

EPO-derived tissue protection

Also known as: ARA 290 · Cibinetide · pHBSP

No account · this device only

The essentials at a glance

Classification
Peptide · Tissue & repair
Mechanism
Non-haematopoietic erythropoietin-derived tissue-protective peptide
Evidence
In clinical trials
Status
In clinical research

Studied clinically for inflammatory, nerve and metabolic outcomes; it lacks general medicinal approval.

Distinction: ARA-290 is derived from erythropoietin but acts without its blood-forming effect, unlike classic EPO products.

Prohibited or covered under WADA rules in competitive sport.

Evidence strengthIn clinical trials

The substance is currently being studied in structured human clinical trials, but a general approval does not yet exist.

In clinical research: A clinical-development candidate, not an approved medicinal product.

Research questions

Mechanism: ARA-290 / Cibinetide

01

EPO-derived tissue protection

This studies whether a fragment derived from erythropoietin can convey tissue protection without the blood-forming activity of the original hormone, similar to a piece that retains only one of several functions. Cell survival and inflammation markers are measured in lab models.

02

Neuroprotective signalling

This examines whether a substance can protect nerve cells from stress or damage, such as after oxygen deprivation in a cell model. Cell survival and signalling markers in nerve tissue under lab conditions are measured.

03

Immune-modulating peptide

This studies how a peptide adjusts immune cell activity, similar to a dial that strengthens or dampens the immune response. Immune cell counts and inflammation markers are measured in studies.

Simple example

Research-only molecule

Think of it like a component still being tested in a development workshop, not yet cleared for general use.

Research status means efficacy, dosing, and safety in humans are not yet conclusively established.

Community themes

How communities discuss it

Personal experience reports and vendor marketing from communities are not scientific proof of efficacy.

Recovery and injury forums

Personal recovery times after sports injuries while using different repair peptides are compared, often based on subjective pain scales. Such individual courses are influenced by many other factors and do not prove efficacy.

Biohacker and longevity forums

Users compare self-assembled combinations of peptides aimed at influencing ageing processes or energy levels, often based on blood tests or subjective wellbeing scales. Personal self-experiments and marketing promises do not replace controlled long-term human studies.

Source and purity discussion

Discussion covers which vendors are seen as more trustworthy and how purity test results differ between batches. Such community assessments are based on limited samples and do not replace independent lab testing of each individual batch.

Evidence boundary

General medicinal approval is lacking despite clinical study.

No peptide sales or individual recommendations. A separately labelled community area documents third-party protocol claims without medically endorsing them.

Primary sources

Regulators, trial registries and scientific databases support the classification and carry more weight than vendor or community claims.